Your allergies
aren't random.
They're genetic.
Upload your DNA. We map the 7 steps of your allergic cascade, find the genetic weak points, and build a protocol targeting your vulnerabilities.
Generic advice. Generic results.
Your allergic response is a 7-step genetic cascade. Generic solutions only target 1-2 steps. You're missing the other five.
Wrong targets
Taking DAO enzymes when your bottleneck is mast cell activation? Money wasted on supplements that can't help your specific genetics.
Incomplete picture
Most protocols address histamine clearance alone. But what about the 6 other cascade steps that determine how much histamine floods your system?
Not personalized
Your DNA says which cascade steps are weakest — and exactly where to intervene. Generic advice ignores this entirely.
The 7-Step Allergic Cascade
Every allergic reaction follows this sequence. Your genetics create bottlenecks at different steps.
Three steps to your decoded protocol
Upload your DNA
Export your raw data from 23andMe, AncestryDNA, or SelfDecode. Drag, drop, done. We extract ~50 allergy-relevant SNPs.
Map your cascade
Our algorithm scores each of the 7 cascade steps based on your specific genetic variants. See exactly where your response breaks down.
Get your protocol
Personalized supplement stack targeting your weakest cascade steps — dosing, timing, loading timeline, and an acute flare plan.
Built because I was tired of being
my own guinea pig.
Every spring, the same routine: wake up congested, pop a Claritin, try quercetin, maybe nettle tea. Some years better than others. Never a clear reason why.
Then I got my DNA sequenced and mapped every allergy-relevant variant. The picture was devastatingly clear: four HRH4 receptor variants, compromised DAO clearance, weak SOD2 defense, and elevated baseline inflammation from MTHFR.
Generic supplements were targeting one step. I had vulnerabilities at five of seven.
AllerGenome automates what took me weeks of research into a 15-minute upload.
Anthony Scarpulla
Founder · Test case #1
One report. Lifetime insights.
Your DNA doesn't change. One-time purchase for permanent genetic intelligence.
Your complete genetic allergy protocol. Less than a doctor's copay.
DNA encrypted at rest · Deleted after processing · Never shared
What your protocol looks like
Your genetic profile reveals significant vulnerabilities in Steps 2 (Alarm Signals), 4 (Histamine Response), 5 (Clearance), and 6 (Oxidative Stress). Your HRH4 receptor variants make you hypersensitive to histamine, while compromised DAO clearance means it lingers longer than normal. Combined with weak SOD2 antioxidant defense, each allergic episode creates oxidative damage that amplifies the next one.
Blocks IL-33 signaling (Step 2) — your TSLP/IL-33 variants amplify alarm signals
Directly inhibits STAT6 mast cell activation (Step 3) — needs 5+ weeks loading
Downregulates HLA overexpression (Step 1) — your HLA-DQA1 variant flags harmless allergens
Supports DAO enzyme function (Step 5) + mast cell stabilization (Step 3)
Compensates for your DAO/AOC1 rs2052129 GT variant — slow histamine clearance (Step 5)
Reduces IL-6 baseline inflammation (Step 7) — your IL-6 rs1800795 GC variant elevates baseline
Glutathione precursor for your compromised SOD2 AA genotype (Step 6)
Broad anti-inflammatory targeting Step 7 baseline — pairs with your MTHFR support
Bypasses your MTHFR A1298C GG variant (Step 7) — supports methylation cycle